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Ventromedial hypothalamic OGT drives adipose tissue lipolysis and curbs obesity
The ventromedial hypothalamus (VMH) is known to regulate body weight and counterregulatory response. However, how VMH neurons regulate lipid metabolism and energy balance remains unknown. O-linked β-d-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation), catalyzed by O-GlcNAc transferase (O...
Autores principales: | Wang, Qi, Zhang, Bichen, Stutz, Bernardo, Liu, Zhong-Wu, Horvath, Tamas L., Yang, Xiaoyong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432828/ https://www.ncbi.nlm.nih.gov/pubmed/36044565 http://dx.doi.org/10.1126/sciadv.abn8092 |
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