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Spatiotemporal NF-κB dynamics encodes the position, amplitude, and duration of local immune inputs

Infected cells communicate through secreted signaling molecules like cytokines, which carry information about pathogens. How differences in cytokine secretion affect inflammatory signaling over space and how responding cells decode information from propagating cytokines are not understood. By comput...

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Detalles Bibliográficos
Autores principales: Son, Minjun, Frank, Tino, Holst-Hansen, Thomas, Wang, Andrew G., Junkin, Michael, Kashaf, Sara S., Trusina, Ala, Tay, Savaş
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432835/
https://www.ncbi.nlm.nih.gov/pubmed/36044569
http://dx.doi.org/10.1126/sciadv.abn6240