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An ex vivo culture model of kidney podocyte injury reveals mechanosensitive, synaptopodin-templating, sarcomere-like structures

Chronic kidney diseases are widespread and incurable. The biophysical mechanisms underlying them are unclear, in part because material systems for reconstituting the microenvironment of relevant kidney cells are limited. A critical question is how kidney podocytes (glomerular epithelial cells) regen...

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Detalles Bibliográficos
Autores principales: Jiang, Shumeng, Alisafaei, Farid, Huang, Yin-Yuan, Hong, Yuan, Peng, Xiangjun, Qu, Chengqing, Puapatanakul, Pongpratch, Jain, Sanjay, Miner, Jeffrey H., Genin, Guy M., Suleiman, Hani Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432837/
https://www.ncbi.nlm.nih.gov/pubmed/36044576
http://dx.doi.org/10.1126/sciadv.abn6027