Operation of a TCA cycle subnetwork in the mammalian nucleus

Nucleic acid and histone modifications critically depend on the tricarboxylic acid (TCA) cycle for substrates and cofactors. Although a few TCA cycle enzymes have been reported in the nucleus, the corresponding pathways are considered to operate in mitochondria. Here, we show that a part of the TCA...

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Detalles Bibliográficos
Autores principales: Kafkia, Eleni, Andres-Pons, Amparo, Ganter, Kerstin, Seiler, Markus, Smith, Tom S., Andrejeva, Anna, Jouhten, Paula, Pereira, Filipa, Franco, Catarina, Kuroshchenkova, Anna, Leone, Sergio, Sawarkar, Ritwick, Boston, Rebecca, Thaventhiran, James, Zaugg, Judith B., Lilley, Kathryn S., Lancrin, Christophe, Beck, Martin, Patil, Kiran Raosaheb
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432838/
https://www.ncbi.nlm.nih.gov/pubmed/36044572
http://dx.doi.org/10.1126/sciadv.abq5206

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