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Folic acid restricts SARS-CoV-2 invasion by methylating ACE2

The current COVID-19 pandemic is motivating us to elucidate the molecular mechanism of SARS-CoV-2 invasion and find methods for decreasing its transmissibility. We found that SARS-CoV-2 could increase the protein level of ACE2 in mice. Folic acid and 5-10-methylenetetrahydrofolate reductase (MTHFR)...

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Detalles Bibliográficos
Autores principales:	Zhang, Yuanzhou, Pang, Yechun, Xu, Baiyin, Chen, Xingshi, Liang, Shunshun, Hu, Jingying, Luo, Xiaoying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9432853/ https://www.ncbi.nlm.nih.gov/pubmed/36060767 http://dx.doi.org/10.3389/fmicb.2022.980903

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