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Tissue-specific modifier alleles determine Mertk loss-of-function traits

Knockout (KO) mouse models play critical roles in elucidating biological processes behind disease-associated or disease-resistant traits. As a presumed consequence of gene KO, mice display certain phenotypes. Based on insight into the molecular role of said gene in a biological process, it is inferr...

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Detalles Bibliográficos
Autores principales: Akalu, Yemsratch T, Mercau, Maria E, Ansems, Marleen, Hughes, Lindsey D, Nevin, James, Alberto, Emily J, Liu, Xinran N, He, Li-Zhen, Alvarado, Diego, Keler, Tibor, Kong, Yong, Philbrick, William M, Bosenberg, Marcus, Finnemann, Silvia C, Iavarone, Antonio, Lasorella, Anna, Rothlin, Carla V, Ghosh, Sourav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433089/
https://www.ncbi.nlm.nih.gov/pubmed/35969037
http://dx.doi.org/10.7554/eLife.80530

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