Longitudinal analysis reveals age-related changes in the T cell receptor repertoire of human T cell subsets

A diverse T cell receptor (TCR) repertoire is essential for protection against a variety of pathogens, and TCR repertoire size is believed to decline with age. However, the precise size of human TCR repertoires, in both total and subsets of T cells, as well as their changes with age, are not fully c...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoping, Nguyen, Thomas, Achour, Achouak, Ko, Annette, Cifello, Jeffrey, Ling, Chen, Sharma, Jay, Hiroi, Toyoko, Zhang, Yongqing, Chia, Chee W., Wood, William, Wu, Wells W., Zukley, Linda, Phue, Je-Nie, Becker, Kevin G., Shen, Rong-Fong, Ferrucci, Luigi, Weng, Nan-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433102/
https://www.ncbi.nlm.nih.gov/pubmed/35708913
http://dx.doi.org/10.1172/JCI158122

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