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SOCS3 Attenuates Dexamethasone-Induced M2 Polarization by Down-Regulation of GILZ via ROS- and p38 MAPK-Dependent Pathways

Suppressors of cytokine signaling (SOCS) have emerged as potential regulators of macrophage function. We have investigated mechanisms of SOCS3 action on type 2 macrophage (M2) differentiation induced by glucocorticoid using human monocytic cell lines and mouse bone marrow-derived macrophages. Treatm...

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Detalles Bibliográficos
Autores principales: Jeong, Hana, Yoon, Hyeyoung, Lee, Yerin, Kim, Jun Tae, Yang, Moses, Kim, Gayoung, Jung, Bom, Park, Seok Hee, Lee, Choong-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433193/
https://www.ncbi.nlm.nih.gov/pubmed/36081527
http://dx.doi.org/10.4110/in.2022.22.e33