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A mitotic chromatin phase transition prevents perforation by microtubules
Dividing eukaryotic cells package extremely long chromosomal DNA molecules into discrete bodies to enable microtubule-mediated transport of one genome copy to each of the newly forming daughter cells(1–3). Assembly of mitotic chromosomes involves DNA looping by condensin(4–8) and chromatin compactio...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433320/ https://www.ncbi.nlm.nih.gov/pubmed/35922507 http://dx.doi.org/10.1038/s41586-022-05027-y |