A mitotic chromatin phase transition prevents perforation by microtubules

Dividing eukaryotic cells package extremely long chromosomal DNA molecules into discrete bodies to enable microtubule-mediated transport of one genome copy to each of the newly forming daughter cells(1–3). Assembly of mitotic chromosomes involves DNA looping by condensin(4–8) and chromatin compactio...

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Detalles Bibliográficos
Autores principales: Schneider, Maximilian W. G., Gibson, Bryan A., Otsuka, Shotaro, Spicer, Maximilian F. D., Petrovic, Mina, Blaukopf, Claudia, Langer, Christoph C. H., Batty, Paul, Nagaraju, Thejaswi, Doolittle, Lynda K., Rosen, Michael K., Gerlich, Daniel W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433320/
https://www.ncbi.nlm.nih.gov/pubmed/35922507
http://dx.doi.org/10.1038/s41586-022-05027-y

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