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Suppression of PFKFB3-driven glycolysis restrains endothelial-to-mesenchymal transition and fibrotic response

Endothelial-to-mesenchymal transition (EndoMT), the process wherein endothelial cells lose endothelial identity and adopt mesenchymal-like phenotypes, constitutes a critical contributor to cardiac fibrosis. The phenotypic plasticity of endothelial cells can be intricately shaped by alteration of met...

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Detalles Bibliográficos
Autores principales:	Zeng, Hao, Pan, Ting, Zhan, Meiling, Hailiwu, Renaguli, Liu, Baolin, Yang, Hua, Li, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433407/ https://www.ncbi.nlm.nih.gov/pubmed/36045132 http://dx.doi.org/10.1038/s41392-022-01097-6

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