Induction of RAC1 protein translation and MKK7/JNK-dependent autophagy through dicer/miR-145/SOX2/miR-365a axis contributes to isorhapontigenin (ISO) inhibition of human bladder cancer invasion

Although our previous studies have identified that isorhapontigenin (ISO) is able to initiate autophagy in human bladder cancer (BC) cells by activating JNK/C-Jun/SESN2 axis and possesses an inhibitory effect on BC cell growth, association of autophagy directly with inhibition of BC invasion has nev...

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Detalles Bibliográficos
Autores principales: Hua, Xiaohui, Xiang, Daimin, Guo, Mengxin, Qian, Xiaohui, Chen, Ruifan, Li, Tengda, Tian, Zhongxian, Xu, Jiheng, Huang, Chao, Xie, Qipeng, Huang, Chuanshu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433410/
https://www.ncbi.nlm.nih.gov/pubmed/36045117
http://dx.doi.org/10.1038/s41419-022-05205-w

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