Caspar, an adapter for VAPB and TER94, modulates the progression of ALS8 by regulating IMD/NFκB-mediated glial inflammation in a Drosophila model of human disease

Amyotrophic lateral sclerosis (ALS) is a fatal, late-onset, progressive motor neurodegenerative disorder. A key pathological feature of the disease is the presence of heavily ubiquitinated protein inclusions. Both the unfolded protein response and the ubiquitin–proteasome system appear significantly...

Descripción completa

Detalles Bibliográficos
Autores principales: Tendulkar, Shweta, Hegde, Sushmitha, Garg, Lovleen, Thulasidharan, Aparna, Kaduskar, Bhagyashree, Ratnaparkhi, Anuradha, Ratnaparkhi, Girish S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433731/
https://www.ncbi.nlm.nih.gov/pubmed/35377453
http://dx.doi.org/10.1093/hmg/ddac076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433731/
https://www.ncbi.nlm.nih.gov/pubmed/35377453
http://dx.doi.org/10.1093/hmg/ddac076

Ejemplares similares