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Pressure and curvature control of the cell cycle in epithelia growing under spherical confinement

Morphogenesis requires spatiotemporal regulation of proliferation, both by biochemical and mechanical cues. In epithelia, this regulation is called contact inhibition of proliferation, but disentangling biochemical from mechanical cues remains challenging. Here, we show that epithelia growing under...

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Detalles Bibliográficos
Autores principales: Di Meglio, Ilaria, Trushko, Anastasiya, Guillamat, Pau, Blanch-Mercader, Carles, Abuhattum, Shada, Roux, Aurélien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433880/
https://www.ncbi.nlm.nih.gov/pubmed/36001958
http://dx.doi.org/10.1016/j.celrep.2022.111227