Astrocyte calcium dysfunction causes early network hyperactivity in Alzheimer’s disease

Dysfunctions of network activity and functional connectivity (FC) represent early events in Alzheimer’s disease (AD), but the underlying mechanisms remain unclear. Astrocytes regulate local neuronal activity in the healthy brain, but their involvement in early network hyperactivity in AD is unknown....

Descripción completa

Detalles Bibliográficos
Autores principales: Shah, Disha, Gsell, Willy, Wahis, Jérôme, Luckett, Emma S., Jamoulle, Tarik, Vermaercke, Ben, Preman, Pranav, Moechars, Daan, Hendrickx, Véronique, Jaspers, Tom, Craessaerts, Katleen, Horré, Katrien, Wolfs, Leen, Fiers, Mark, Holt, Matthew, Thal, Dietmar Rudolf, Callaerts-Vegh, Zsuzsanna, D’Hooge, Rudi, Vandenberghe, Rik, Himmelreich, Uwe, Bonin, Vincent, De Strooper, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433881/
https://www.ncbi.nlm.nih.gov/pubmed/36001964
http://dx.doi.org/10.1016/j.celrep.2022.111280

Ejemplares similares

Ejemplares similares