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CAR-T cell development for Cutaneous T cell Lymphoma: current limitations and potential treatment strategies

Chimeric antigen receptor (CAR)-T therapy has demonstrated remarkable outcomes for B cell malignancies, however, its application for T cell lymphoma, particularly cutaneous T cell lymphoma (CTCL), has been limited. Barriers to effective CAR-T cell therapy in treating CTCL include T cell aplasia in a...

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Detalles Bibliográficos
Autores principales:	To, Van, Evtimov, Vera J., Jenkin, Graham, Pupovac, Aleta, Trounson, Alan O., Boyd, Richard L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433932/ https://www.ncbi.nlm.nih.gov/pubmed/36059451 http://dx.doi.org/10.3389/fimmu.2022.968395

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