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Long Noncoding RNA MIR4435-2HG Suppresses Colorectal Cancer Initiation and Progression By Reprogramming Neutrophils

MIR4435-2HG, also known as LINC00978, has previously been described as an oncogenic long noncoding RNA (lncRNA). However, we show here that Mir4435-2hg depletion promoted colorectal tumorigenesis and progression in in vivo models of colitis-associated colorectal cancer, spontaneous intestinal adenom...

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Detalles Bibliográficos
Autores principales:	Yu, Hongfei, Chen, Chaoyi, Han, Fengyan, Tang, Jinlong, Deng, Mengli, Niu, Yumiao, Lai, Maode, Zhang, Honghe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9433964/ https://www.ncbi.nlm.nih.gov/pubmed/35862232 http://dx.doi.org/10.1158/2326-6066.CIR-21-1011

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