AIFM1 is a component of the mitochondrial disulfide relay that drives complex I assembly through efficient import of NDUFS5

The mitochondrial intermembrane space protein AIFM1 has been reported to mediate the import of MIA40/CHCHD4, which forms the import receptor in the mitochondrial disulfide relay. Here, we demonstrate that AIFM1 and MIA40/CHCHD4 cooperate beyond this MIA40/CHCHD4 import. We show that AIFM1 and MIA40/...

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Autores principales: Salscheider, Silja Lucia, Gerlich, Sarah, Cabrera‐Orefice, Alfredo, Peker, Esra, Rothemann, Robin Alexander, Murschall, Lena Maria, Finger, Yannik, Szczepanowska, Karolina, Ahmadi, Zeinab Alsadat, Guerrero‐Castillo, Sergio, Erdogan, Alican, Becker, Mark, Ali, Muna, Habich, Markus, Petrungaro, Carmelina, Burdina, Nele, Schwarz, Guenter, Klußmann, Merlin, Neundorf, Ines, Stroud, David A, Ryan, Michael T, Trifunovic, Aleksandra, Brandt, Ulrich, Riemer, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434101/
https://www.ncbi.nlm.nih.gov/pubmed/35859387
http://dx.doi.org/10.15252/embj.2022110784

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