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Mechanisms underlying DMARD inefficacy in difficult-to-treat rheumatoid arthritis: a narrative review with systematic literature search

Management of RA patients has significantly improved over the past decades. However, a substantial proportion of patients is difficult-to-treat (D2T), remaining symptomatic after failing biological and/or targeted synthetic DMARDs. Multiple factors can contribute to D2T RA, including treatment non-a...

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Detalles Bibliográficos
Autores principales: Roodenrijs, Nadia M T, Welsing, Paco M J, van Roon, Joël, Schoneveld, Jan L M, van der Goes, Marlies C, Nagy, György, Townsend, Michael J, van Laar, Jacob M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434144/
https://www.ncbi.nlm.nih.gov/pubmed/35238332
http://dx.doi.org/10.1093/rheumatology/keac114