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Modular safe-harbor transgene insertion for targeted single-copy and extrachromosomal array integration in Caenorhabditis elegans
Efficient and reproducible transgenesis facilitates and accelerates research using genetic model organisms. Here, we describe a modular safe-harbor transgene insertion (MosTI) for use in Caenorhabditis elegans which improves targeted insertion of single-copy transgenes by homology directed repair an...
Autores principales: | El Mouridi, Sonia, Alkhaldi, Faisal, Frøkjær-Jensen, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434227/ https://www.ncbi.nlm.nih.gov/pubmed/35900171 http://dx.doi.org/10.1093/g3journal/jkac184 |
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