A role for the Saccharomyces cerevisiae Rtt109 histone acetyltransferase in R-loop homeostasis and associated genome instability

The stability of the genome is occasionally challenged by the formation of DNA–RNA hybrids and R-loops, which can be influenced by the chromatin context. This is mainly due to the fact that DNA–RNA hybrids hamper the progression of replication forks, leading to fork stalling and, ultimately, DNA bre...

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Detalles Bibliográficos
Autores principales: Cañas, Juan Carlos, García-Rubio, María Luisa, García, Alicia, Antequera, Francisco, Gómez-González, Belén, Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434296/
https://www.ncbi.nlm.nih.gov/pubmed/35866610
http://dx.doi.org/10.1093/genetics/iyac108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434296/
https://www.ncbi.nlm.nih.gov/pubmed/35866610
http://dx.doi.org/10.1093/genetics/iyac108

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