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Local genetic covariance between serum urate and kidney function estimated with Bayesian multitrait models

Hyperuricemia (serum urate >6.8 mg/dl) is associated with several cardiometabolic and renal diseases, such as gout and chronic kidney disease. Previous studies have examined the shared genetic basis of chronic kidney disease and hyperuricemia in humans either using single-variant tests or estimat...

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Detalles Bibliográficos
Autores principales: Lupi, Alexa S, Sumpter, Nicholas A, Leask, Megan P, O’Sullivan, Justin, Fadason, Tayaza, de los Campos, Gustavo, Merriman, Tony R, Reynolds, Richard J, Vazquez, Ana I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434310/
https://www.ncbi.nlm.nih.gov/pubmed/35876900
http://dx.doi.org/10.1093/g3journal/jkac158