Cargando…
Human endothelial cell-derived exosomal microRNA-99a/b drives a sustained inflammatory response during sepsis by inhibiting mTOR expression
The pathophysiology of sepsis and its accompanying hyper-inflammatory response are key events that lead to multi-organ failure and death. A growing body of literature now suggests that the vascular endothelium plays a critical role in driving early events of sepsis progression. In this study, we dem...
Autores principales: | Fitzpatrick, Glenn, Nader, Danielle, Watkin, Rebecca, McCoy, Claire E., Curley, Gerard F., Kerrigan, Steven W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434345/ https://www.ncbi.nlm.nih.gov/pubmed/36061862 http://dx.doi.org/10.3389/fcimb.2022.854126 |
Ejemplares similares
-
HIV-1 replication and latency are balanced by mTOR-driven cell metabolism
por: Crater, Jacqueline M., et al.
Publicado: (2022) -
Mycobacterium tuberculosis Calcium Pump CtpF Modulates the Autophagosome in an mTOR-Dependent Manner
por: Garg, Rajni, et al.
Publicado: (2020) -
A new perspective in sepsis treatment: could RGD-dependent integrins be novel targets?
por: Nader, Danielle, et al.
Publicado: (2020) -
Dengue Virus Dysregulates Master Transcription Factors and PI3K/AKT/mTOR Signaling Pathway in Megakaryocytes
por: Lahon, Anismrita, et al.
Publicado: (2021) -
Integrins as Therapeutic Targets for SARS-CoV-2
por: Gressett, Timothy E., et al.
Publicado: (2022)