Cargando…

Human endothelial cell-derived exosomal microRNA-99a/b drives a sustained inflammatory response during sepsis by inhibiting mTOR expression

The pathophysiology of sepsis and its accompanying hyper-inflammatory response are key events that lead to multi-organ failure and death. A growing body of literature now suggests that the vascular endothelium plays a critical role in driving early events of sepsis progression. In this study, we dem...

Descripción completa

Detalles Bibliográficos
Autores principales: Fitzpatrick, Glenn, Nader, Danielle, Watkin, Rebecca, McCoy, Claire E., Curley, Gerard F., Kerrigan, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434345/
https://www.ncbi.nlm.nih.gov/pubmed/36061862
http://dx.doi.org/10.3389/fcimb.2022.854126

Ejemplares similares