PDPN marks a subset of aggressive and radiation-resistant glioblastoma cells

Treatment-resistant glioma stem cells are thought to propagate and drive growth of malignant gliomas, but their markers and our ability to target them specifically are not well understood. We demonstrate that podoplanin (PDPN) expression is an independent prognostic marker in gliomas across multiple...

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Detalles Bibliográficos
Autores principales: Modrek, Aram S., Eskilsson, Eskil, Ezhilarasan, Ravesanker, Wang, Qianghu, Goodman, Lindsey D., Ding, Yingwen, Zhang, Ze-Yan, Bhat, Krishna P. L., Le, Thanh-Thuy T., Barthel, Floris P., Tang, Ming, Yang, Jie, Long, Lihong, Gumin, Joy, Lang, Frederick F., Verhaak, Roel G. W., Aldape, Kenneth D., Sulman, Erik P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434399/
https://www.ncbi.nlm.nih.gov/pubmed/36059614
http://dx.doi.org/10.3389/fonc.2022.941657

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