Impaired mitochondria of Tregs decreases OXPHOS-derived ATP in primary immune thrombocytopenia with positive plasma pathogens detected by metagenomic sequencing

BACKGROUND: Primary immune thrombocytopenia (ITP) is an autoimmune disease. Some ITP patients are associated with pathogen infection undetected with conventional technologies. Investigating the changes of T cells and potential metabolic mechanism are important for better understanding of ITP. METHOD...

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Detalles Bibliográficos
Autores principales: Zhan, Yanxia, Cao, Jingjing, Ji, Lili, Zhang, Miaomiao, Shen, Qi, Xu, Pengcheng, Zhuang, Xibing, Qin, Shanshan, Hua, Fanli, Sun, Lihua, Li, Feng, Chen, Hao, Cheng, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434515/
https://www.ncbi.nlm.nih.gov/pubmed/36050760
http://dx.doi.org/10.1186/s40164-022-00304-y

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