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Fractional-order model on vaccination and severity of COVID-19

Coronavirus disease 2019 (COVID-19), an infection that is highly contagious. It has a regrettable effect on the world and has resulted in more than 4.6 million deaths to date (July 2021). For this contagious disease, numerous nations implemented control measures. Every country has vaccination progra...

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Autores principales: Shah, Nita H., Jayswal, Ekta N., Suthar, Ankush H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434535/
https://www.ncbi.nlm.nih.gov/pubmed/36065200
http://dx.doi.org/10.1007/s40435-022-01023-2
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author Shah, Nita H.
Jayswal, Ekta N.
Suthar, Ankush H.
author_facet Shah, Nita H.
Jayswal, Ekta N.
Suthar, Ankush H.
author_sort Shah, Nita H.
collection PubMed
description Coronavirus disease 2019 (COVID-19), an infection that is highly contagious. It has a regrettable effect on the world and has resulted in more than 4.6 million deaths to date (July 2021). For this contagious disease, numerous nations implemented control measures. Every country has vaccination programs in place to achieve the best results. This research is done in two stages, including partial and complete vaccination, to enhance the efficiency and effectiveness of the vaccination. Our study found that receiving this vaccination lowers the risk of contracting a disease and its side effects, such as severity, hospitalization, need for oxygen, admission to the intensive care unit, and infection-related death. Taking into account, the system is built using fractional-order Caputo sense nonlinear differential equations. A basic reproduction number is calculated to determine the transmission rate. The bifurcation analysis predicts chaotic behavior of a system for this threshold value. The suggested system's recovery rate is optimized using fractional optimum controls. For the fractional-order differential equation, numerical results are simulated using MATLAB software using real-validated data (July 2021).
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spelling pubmed-94345352022-09-01 Fractional-order model on vaccination and severity of COVID-19 Shah, Nita H. Jayswal, Ekta N. Suthar, Ankush H. Int J Dyn Control Article Coronavirus disease 2019 (COVID-19), an infection that is highly contagious. It has a regrettable effect on the world and has resulted in more than 4.6 million deaths to date (July 2021). For this contagious disease, numerous nations implemented control measures. Every country has vaccination programs in place to achieve the best results. This research is done in two stages, including partial and complete vaccination, to enhance the efficiency and effectiveness of the vaccination. Our study found that receiving this vaccination lowers the risk of contracting a disease and its side effects, such as severity, hospitalization, need for oxygen, admission to the intensive care unit, and infection-related death. Taking into account, the system is built using fractional-order Caputo sense nonlinear differential equations. A basic reproduction number is calculated to determine the transmission rate. The bifurcation analysis predicts chaotic behavior of a system for this threshold value. The suggested system's recovery rate is optimized using fractional optimum controls. For the fractional-order differential equation, numerical results are simulated using MATLAB software using real-validated data (July 2021). Springer Berlin Heidelberg 2022-09-01 2023 /pmc/articles/PMC9434535/ /pubmed/36065200 http://dx.doi.org/10.1007/s40435-022-01023-2 Text en © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Article
Shah, Nita H.
Jayswal, Ekta N.
Suthar, Ankush H.
Fractional-order model on vaccination and severity of COVID-19
title Fractional-order model on vaccination and severity of COVID-19
title_full Fractional-order model on vaccination and severity of COVID-19
title_fullStr Fractional-order model on vaccination and severity of COVID-19
title_full_unstemmed Fractional-order model on vaccination and severity of COVID-19
title_short Fractional-order model on vaccination and severity of COVID-19
title_sort fractional-order model on vaccination and severity of covid-19
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434535/
https://www.ncbi.nlm.nih.gov/pubmed/36065200
http://dx.doi.org/10.1007/s40435-022-01023-2
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