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Plasma biomarkers predict cognitive trajectories in an ethnoracially and clinically diverse cohort: Mediation with hippocampal volume

INTRODUCTION: We examine whether the association between key plasma biomarkers (amyloid β [aβ] 42/40, total tau (t‐tau), neurofilament light [NfL]) and cognitive trajectories (executive function [EF] and episodic memory [EM]) is mediated through neurodegeneration. METHODS: All participants were recr...

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Detalles Bibliográficos
Autores principales: Sapkota, Shraddha, Erickson, Kelsey, Harvey, Danielle, Tomaszewski‐Farias, Sarah E., Olichney, John M., Johnson, David K., Dugger, Brittany N., Mungas, Dan M., Fletcher, Evan, Maillard, Pauline, Seshadri, Sudha, Satizabal, Claudia L., Kautz, Tiffany, Parent, Danielle, Tracy, Russell P., Maezawa, Izumi, Jin, Lee‐Way, DeCarli, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434579/
https://www.ncbi.nlm.nih.gov/pubmed/36092690
http://dx.doi.org/10.1002/dad2.12349