Isoxazole Derivatives against Carbonic Anhydrase: Synthesis, Molecular Docking, MD Simulations, and Free Energy Calculations Coupled with In Vitro Studies

[Image: see text] Heterocyclic compounds with a five-membered ring as a core, particularly those containing more than one heteroatom, have a wide spectrum of biological functions, especially in enzyme inhibition. In this study, we present the synthesis of five-membered heterocyclic isoxazole derivat...

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Detalles Bibliográficos
Autores principales: Saleem, Afia, Farooq, Umar, Bukhari, Syed Majid, Khan, Sara, Zaidi, Asma, Wani, Tanveer A., Shaikh, Ahson Jabbar, Sarwar, Rizwana, Mahmud, Shafi, Israr, Muhammad, Khan, Farhan A., Shahzad, Sohail Anjum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434621/
https://www.ncbi.nlm.nih.gov/pubmed/36061660
http://dx.doi.org/10.1021/acsomega.2c03600

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