The sequential natalizumab – alemtuzumab therapy in patients with relapsing forms of multiple sclerosis (SUPPRESS) trial – Part I: Rationale and objectives

BACKGROUND: Natalizumab is a recombinant humanized monoclonal antibody (mAb) against α4-integrin that is approved for relapsing forms of multiple sclerosis (MS). Natalizumab is associated with an increased risk of developing progressive multifocal leukoencephalopathy (PML), and with disease reactiva...

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Detalles Bibliográficos
Autores principales: Hussain, Rehana Z, Sguigna, Peter V, Okai, Annette, Wright, Crystal, Madinawala, Mariam, Bass, Ann D, Cutter, Gary R, Manouchehri, Navid, Stuve, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434668/
https://www.ncbi.nlm.nih.gov/pubmed/36062026
http://dx.doi.org/10.1177/11795735221123911

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