Synthesis and In Vitro Evaluation of a Set of 6-Deoxy-6-thio-carboranyl d-Glucoconjugates Shed Light on the Substrate Specificity of the GLUT1 Transporter

[Image: see text] Glucose- and sodium-dependent glucose transporters (GLUTs and SGLTs) play vital roles in human biology. Of the 14 GLUTs and 12 SGLTs, the GLUT1 transporter has gained the most widespread recognition because GLUT1 is overexpressed in several cancers and is a clinically valid therape...

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Detalles Bibliográficos
Autores principales: Matović, Jelena, Järvinen, Juulia, Sokka, Iris K., Stockmann, Philipp, Kellert, Martin, Imlimthan, Surachet, Sarparanta, Mirkka, Johansson, Mikael P., Hey-Hawkins, Evamarie, Rautio, Jarkko, Ekholm, Filip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434784/
https://www.ncbi.nlm.nih.gov/pubmed/36061667
http://dx.doi.org/10.1021/acsomega.2c03646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434784/
https://www.ncbi.nlm.nih.gov/pubmed/36061667
http://dx.doi.org/10.1021/acsomega.2c03646

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