α-Dystrobrevin knockout mice have increased motivation for appetitive reward and altered brain cannabinoid receptor 1 expression

α-Dystrobrevin (α-DB) is a major component of the dystrophin-associated protein complex (DAPC). Knockout (KO) of α-DB in the brain is associated with astrocytic abnormalities and loss of neuronal GABA receptor clustering. Mutations in DAPC proteins are associated with altered dopamine signaling and...

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Detalles Bibliográficos
Autores principales: Hawkes, Cheryl A., Heath, Christopher J., Sharp, Matthew M., Górecki, Dariusz C., Carare, Roxana O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434862/
https://www.ncbi.nlm.nih.gov/pubmed/36045406
http://dx.doi.org/10.1186/s40478-022-01434-4

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