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APE1 redox function is required for activation of Yes-associated protein 1 under reflux conditions in Barrett’s-associated esophageal adenocarcinomas

BACKGROUND: Esophageal adenocarcinoma (EAC) is characterized by poor prognosis and low survival rate. Chronic gastroesophageal reflux disease (GERD) is the main risk factor for the development of Barrett’s esophagus (BE), a preneoplastic metaplastic condition, and its progression to EAC. Yes-associa...

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Detalles Bibliográficos
Autores principales:	Ballout, Farah, Lu, Heng, Chen, Lei, Sriramajayam, Kannappan, Que, Jianwen, Meng, Zhipeng, Wang, Timothy C., Giordano, Silvia, Zaika, Alexander, McDonald, Oliver, Peng, Dunfa, El-Rifai, Wael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434868/ https://www.ncbi.nlm.nih.gov/pubmed/36045416 http://dx.doi.org/10.1186/s13046-022-02472-5

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