Genome-wide interrogation of structural variation reveals novel African-specific prostate cancer oncogenic drivers

BACKGROUND: African ancestry is a significant risk factor for advanced prostate cancer (PCa). Mortality rates in sub-Saharan Africa are 2.5-fold greater than global averages. However, the region has largely been excluded from the benefits of whole genome interrogation studies. Additionally, while st...

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Detalles Bibliográficos
Autores principales: Gong, Tingting, Jaratlerdsiri, Weerachai, Jiang, Jue, Willet, Cali, Chew, Tracy, Patrick, Sean M., Lyons, Ruth J., Haynes, Anne-Maree, Pasqualim, Gabriela, Brum, Ilma Simoni, Stricker, Phillip D., Mutambirwa, Shingai B. A., Sadsad, Rosemarie, Papenfuss, Anthony T., Bornman, Riana M. S., Chan, Eva K. F., Hayes, Vanessa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434886/
https://www.ncbi.nlm.nih.gov/pubmed/36045381
http://dx.doi.org/10.1186/s13073-022-01096-w

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