Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus

Coronavirus disease (COVID-19) in immunocompromised patients represents a major challenge for diagnostics, surveillance, and treatment. Some individuals remain SARS-CoV-2 PCR-positive for a prolonged period. The clinical and epidemiological significance of this phenomenon is not well understood. We...

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Autores principales: Veličković, Jelena, Vukičević, Tatjana Adžić, Spurnić, Aleksandra Radovanović, Lazić, Igor, Popović, Bojana, Bogdanović, Ivan, Raičević, Savo, Marić, Dragana, Berisavac, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434960/
https://www.ncbi.nlm.nih.gov/pubmed/36059827
http://dx.doi.org/10.3389/fmed.2022.973817
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author Veličković, Jelena
Vukičević, Tatjana Adžić
Spurnić, Aleksandra Radovanović
Lazić, Igor
Popović, Bojana
Bogdanović, Ivan
Raičević, Savo
Marić, Dragana
Berisavac, Ivana
author_facet Veličković, Jelena
Vukičević, Tatjana Adžić
Spurnić, Aleksandra Radovanović
Lazić, Igor
Popović, Bojana
Bogdanović, Ivan
Raičević, Savo
Marić, Dragana
Berisavac, Ivana
author_sort Veličković, Jelena
collection PubMed
description Coronavirus disease (COVID-19) in immunocompromised patients represents a major challenge for diagnostics, surveillance, and treatment. Some individuals remain SARS-CoV-2 PCR-positive for a prolonged period. The clinical and epidemiological significance of this phenomenon is not well understood. We report a case of a patient with a history of systemic lupus erythematosus (SLE) who has been persistently SARS-CoV-2 PCR positive for 9 months, with multiple thromboembolic complications, and development of nocardial brain abscess successfully treated with surgery and antibiotics.
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spelling pubmed-94349602022-09-02 Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus Veličković, Jelena Vukičević, Tatjana Adžić Spurnić, Aleksandra Radovanović Lazić, Igor Popović, Bojana Bogdanović, Ivan Raičević, Savo Marić, Dragana Berisavac, Ivana Front Med (Lausanne) Medicine Coronavirus disease (COVID-19) in immunocompromised patients represents a major challenge for diagnostics, surveillance, and treatment. Some individuals remain SARS-CoV-2 PCR-positive for a prolonged period. The clinical and epidemiological significance of this phenomenon is not well understood. We report a case of a patient with a history of systemic lupus erythematosus (SLE) who has been persistently SARS-CoV-2 PCR positive for 9 months, with multiple thromboembolic complications, and development of nocardial brain abscess successfully treated with surgery and antibiotics. Frontiers Media S.A. 2022-08-18 /pmc/articles/PMC9434960/ /pubmed/36059827 http://dx.doi.org/10.3389/fmed.2022.973817 Text en Copyright © 2022 Veličković, Vukičević, Spurnić, Lazić, Popović, Bogdanović, Raičević, Marić and Berisavac. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Veličković, Jelena
Vukičević, Tatjana Adžić
Spurnić, Aleksandra Radovanović
Lazić, Igor
Popović, Bojana
Bogdanović, Ivan
Raičević, Savo
Marić, Dragana
Berisavac, Ivana
Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus
title Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus
title_full Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus
title_fullStr Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus
title_full_unstemmed Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus
title_short Case report: Nocardial brain abscess in a persistently SARS-CoV-2 PCR positive patient with systemic lupus erythematosus
title_sort case report: nocardial brain abscess in a persistently sars-cov-2 pcr positive patient with systemic lupus erythematosus
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9434960/
https://www.ncbi.nlm.nih.gov/pubmed/36059827
http://dx.doi.org/10.3389/fmed.2022.973817
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