Synthesis of Novel 2,3-Dihydro-1,5-Benzothiazepines as α-Glucosidase Inhibitors: In Vitro, In Vivo, Kinetic, SAR, Molecular Docking, and QSAR Studies

[Image: see text] In the present study, a series of 2,3-dihydro-1,5-benzothiazepine derivatives 1B–14B has been synthesized sand characterized by various spectroscopic techniques. The enzyme inhibitory activities of the target analogues were assessed using in vitro and in vivo mechanism-based assays...

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Detalles Bibliográficos
Autores principales: Mehmood, Rabia, Mughal, Ehsan Ullah, Elkaeed, Eslam B., Obaid, Rami J., Nazir, Yasir, Al-Ghulikah, Hanan A., Naeem, Nafeesa, Al-Rooqi, Munirah M., Ahmed, Saleh A., Shah, Syed Wadood Ali, Sadiq, Amina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435035/
https://www.ncbi.nlm.nih.gov/pubmed/36061741
http://dx.doi.org/10.1021/acsomega.2c03328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435035/
https://www.ncbi.nlm.nih.gov/pubmed/36061741
http://dx.doi.org/10.1021/acsomega.2c03328

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