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Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment
Experiments on event-related electroencephalographic oscillations in aged people typically include blocks of cognitive tasks with a few minutes of interval between them. The present exploratory study tested the effect of being engaged on cognitive tasks over the resting state cortical arousal after...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435320/ https://www.ncbi.nlm.nih.gov/pubmed/36062151 http://dx.doi.org/10.3389/fnagi.2022.907130 |
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author | Fernández, Alba Noce, Giuseppe Del Percio, Claudio Pinal, Diego Díaz, Fernando Lojo-Seoane, Cristina Zurrón, Montserrat Babiloni, Claudio |
author_facet | Fernández, Alba Noce, Giuseppe Del Percio, Claudio Pinal, Diego Díaz, Fernando Lojo-Seoane, Cristina Zurrón, Montserrat Babiloni, Claudio |
author_sort | Fernández, Alba |
collection | PubMed |
description | Experiments on event-related electroencephalographic oscillations in aged people typically include blocks of cognitive tasks with a few minutes of interval between them. The present exploratory study tested the effect of being engaged on cognitive tasks over the resting state cortical arousal after task completion, and whether it differs according to the level of the participant’s cognitive decline. To investigate this issue, we used a local database including data in 30 healthy cognitively unimpaired (CU) persons and 40 matched patients with amnestic mild cognitive impairment (aMCI). They had been involved in 2 memory tasks for about 40 min and underwent resting-state electroencephalographic (rsEEG) recording after 5 min from the task end. eLORETA freeware estimated rsEEG alpha source activity as an index of general cortical arousal. In the CU but not aMCI group, there was a negative correlation between memory tasks performance and posterior rsEEG alpha source activity. The better the memory tasks performance, the lower the posterior alpha activity (i.e., higher cortical arousal). There was also a negative correlation between neuropsychological test scores of global cognitive status and alpha source activity. These results suggest that engagement in memory tasks may perturb background brain arousal for more than 5 min after the tasks end, and that this effect are dependent on participants global cognitive status. Future studies in CU and aMCI groups may cross-validate and extend these results with experiments including (1) rsEEG recordings before memory tasks and (2) post-tasks rsEEG recordings after 5, 15, and 30 min. |
format | Online Article Text |
id | pubmed-9435320 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-94353202022-09-02 Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment Fernández, Alba Noce, Giuseppe Del Percio, Claudio Pinal, Diego Díaz, Fernando Lojo-Seoane, Cristina Zurrón, Montserrat Babiloni, Claudio Front Aging Neurosci Aging Neuroscience Experiments on event-related electroencephalographic oscillations in aged people typically include blocks of cognitive tasks with a few minutes of interval between them. The present exploratory study tested the effect of being engaged on cognitive tasks over the resting state cortical arousal after task completion, and whether it differs according to the level of the participant’s cognitive decline. To investigate this issue, we used a local database including data in 30 healthy cognitively unimpaired (CU) persons and 40 matched patients with amnestic mild cognitive impairment (aMCI). They had been involved in 2 memory tasks for about 40 min and underwent resting-state electroencephalographic (rsEEG) recording after 5 min from the task end. eLORETA freeware estimated rsEEG alpha source activity as an index of general cortical arousal. In the CU but not aMCI group, there was a negative correlation between memory tasks performance and posterior rsEEG alpha source activity. The better the memory tasks performance, the lower the posterior alpha activity (i.e., higher cortical arousal). There was also a negative correlation between neuropsychological test scores of global cognitive status and alpha source activity. These results suggest that engagement in memory tasks may perturb background brain arousal for more than 5 min after the tasks end, and that this effect are dependent on participants global cognitive status. Future studies in CU and aMCI groups may cross-validate and extend these results with experiments including (1) rsEEG recordings before memory tasks and (2) post-tasks rsEEG recordings after 5, 15, and 30 min. Frontiers Media S.A. 2022-08-05 /pmc/articles/PMC9435320/ /pubmed/36062151 http://dx.doi.org/10.3389/fnagi.2022.907130 Text en Copyright © 2022 Fernández, Noce, Del Percio, Pinal, Díaz, Lojo-Seoane, Zurrón and Babiloni. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Aging Neuroscience Fernández, Alba Noce, Giuseppe Del Percio, Claudio Pinal, Diego Díaz, Fernando Lojo-Seoane, Cristina Zurrón, Montserrat Babiloni, Claudio Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
title | Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
title_full | Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
title_fullStr | Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
title_full_unstemmed | Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
title_short | Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
title_sort | resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
topic | Aging Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435320/ https://www.ncbi.nlm.nih.gov/pubmed/36062151 http://dx.doi.org/10.3389/fnagi.2022.907130 |
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