Aging Diminishes Mucociliary Clearance of the Lung

Healthy aging leads to a decrease in mucociliary clearance of the lung. Mucociliary clearance is an essential innate immune defense to protect against inhaled particles and microbes. Mucociliary clearance can be affected by changes in cilia function as well as mucus quantity and qualities. With agin...

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Detalles Bibliográficos
Autor principal: Bailey, Kristina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435381/
https://www.ncbi.nlm.nih.gov/pubmed/36066919
http://dx.doi.org/10.20900/agmr20220005
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author Bailey, Kristina L.
author_facet Bailey, Kristina L.
author_sort Bailey, Kristina L.
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description Healthy aging leads to a decrease in mucociliary clearance of the lung. Mucociliary clearance is an essential innate immune defense to protect against inhaled particles and microbes. Mucociliary clearance can be affected by changes in cilia function as well as mucus quantity and qualities. With aging, cilia beat frequency slows and there are changes to the characteristics of mucus. These decreases in mucociliary clearance may lead to lung infection such as pneumonia or airway diseases such as bronchiectasis or Chronic Obstructive Pulmonary Diseases.
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spelling pubmed-94353812022-09-01 Aging Diminishes Mucociliary Clearance of the Lung Bailey, Kristina L. Adv Geriatr Med Res Article Healthy aging leads to a decrease in mucociliary clearance of the lung. Mucociliary clearance is an essential innate immune defense to protect against inhaled particles and microbes. Mucociliary clearance can be affected by changes in cilia function as well as mucus quantity and qualities. With aging, cilia beat frequency slows and there are changes to the characteristics of mucus. These decreases in mucociliary clearance may lead to lung infection such as pneumonia or airway diseases such as bronchiectasis or Chronic Obstructive Pulmonary Diseases. 2022 2022-06-27 /pmc/articles/PMC9435381/ /pubmed/36066919 http://dx.doi.org/10.20900/agmr20220005 Text en https://creativecommons.org/licenses/by/4.0/Licensee Hapres, London, United Kingdom. This is an open access article distributed under the terms and conditions of Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Bailey, Kristina L.
Aging Diminishes Mucociliary Clearance of the Lung
title Aging Diminishes Mucociliary Clearance of the Lung
title_full Aging Diminishes Mucociliary Clearance of the Lung
title_fullStr Aging Diminishes Mucociliary Clearance of the Lung
title_full_unstemmed Aging Diminishes Mucociliary Clearance of the Lung
title_short Aging Diminishes Mucociliary Clearance of the Lung
title_sort aging diminishes mucociliary clearance of the lung
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435381/
https://www.ncbi.nlm.nih.gov/pubmed/36066919
http://dx.doi.org/10.20900/agmr20220005
work_keys_str_mv AT baileykristinal agingdiminishesmucociliaryclearanceofthelung

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