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Native glycosylation and binding of the antidepressant paroxetine in a low-resolution crystal structure of human myeloperoxidase

Human myeloperoxidase (MPO) utilizes hydrogen peroxide to oxidize organic compounds and as such plays an essential role in cell-component synthesis, in metabolic and elimination pathways, and in the front-line defence against pathogens. Moreover, MPO is increasingly being reported to play a role in...

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Detalles Bibliográficos
Autores principales: Krawczyk, Lucas, Semwal, Shubham, Soubhye, Jalal, Lemri Ouadriri, Salma, Prévost, Martin, Van Antwerpen, Pierre, Roos, Goedele, Bouckaert, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435594/
https://www.ncbi.nlm.nih.gov/pubmed/36048150
http://dx.doi.org/10.1107/S2059798322007082