Bone marrow–confined IL-6 signaling mediates the progression of myelodysplastic syndromes to acute myeloid leukemia

Myelodysplastic syndromes (MDS) are age-related myeloid neoplasms with increased risk of progression to acute myeloid leukemia (AML). The mechanisms of transformation of MDS to AML are poorly understood, especially in relation to the aging microenvironment. We previously established an mDia1/miR-146...

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Detalles Bibliográficos
Autores principales: Mei, Yang, Ren, Kehan, Liu, Yijie, Ma, Annabel, Xia, Zongjun, Han, Xu, Li, Ermin, Tariq, Hamza, Bao, Haiyan, Xie, Xinshu, Zou, Cheng, Zhang, Dingxiao, Li, Zhaofeng, Dong, Lili, Verma, Amit, Lu, Xinyan, Abaza, Yasmin, Altman, Jessica K., Sukhanova, Madina, Yang, Jing, Ji, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435651/
https://www.ncbi.nlm.nih.gov/pubmed/35900794
http://dx.doi.org/10.1172/JCI152673

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