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Structure of angiogenin dimer bound to double-stranded RNA

Angiogenin is an unusual member of the RNase A family and is of great interest in multiple pathological contexts. Although it has been assigned various regulatory roles, its core catalytic function is that of an RNA endonuclease. However, its catalytic efficiency is comparatively low and this has be...

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Detalles Bibliográficos
Autores principales: Sievers, Katharina, Ficner, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9435672/
https://www.ncbi.nlm.nih.gov/pubmed/36048083
http://dx.doi.org/10.1107/S2053230X22008317

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