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Analysis of non-human primate models for evaluating prion disease therapeutic efficacy

Prion disease is a fatal neurodegenerative disease caused by the conformational corruption of the prion protein (PrP), encoded by the prion protein gene (PRNP). While no disease-modifying therapy is currently available, genetic and pharmacological proofs of concept support development of therapies t...

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Detalles Bibliográficos
Autores principales:	Mortberg, Meredith A., Minikel, Eric Vallabh, Vallabh, Sonia M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436048/ https://www.ncbi.nlm.nih.gov/pubmed/35994510 http://dx.doi.org/10.1371/journal.ppat.1010728

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