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Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn(2+)-dependent amidases
Human alkaline ceramidase 3 (ACER3) is one of three alkaline ceramidases (ACERs) that catalyze the conversion of ceramide to sphingosine. ACERs are members of the CREST superfamily of integral-membrane hydrolases. All CREST members conserve a set of three Histidine, one Aspartate, and one Serine res...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436119/ https://www.ncbi.nlm.nih.gov/pubmed/36048828 http://dx.doi.org/10.1371/journal.pone.0271540 |