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AICAR attenuates postoperative abdominal adhesion formation by inhibiting oxidative stress and promoting mesothelial cell repair

BACKGROUND: Postoperative abdominal adhesion is one of most common complications after abdominal operations. 5-aminoimidazole-4-carboxyamide ribonucleoside (AICAR) is an adenosine 5’-monophosphate activated protein kinase (AMPK) pathway agonist that inhibits inflammation, reduces cell fibrosis and c...

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Detalles Bibliográficos
Autores principales:	Wu, Yunhua, Duan, Xianglong, Gao, Zengzhan, Yang, Ni, Xue, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436141/ https://www.ncbi.nlm.nih.gov/pubmed/36048820 http://dx.doi.org/10.1371/journal.pone.0272928

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