A Rare Cause of Upper Gastrointestinal Bleeding: Sarcina ventriculi

We describe a patient who presented with hematemesis and was found to have unusually well-demarcated erythematous mucosa with a 2–3 cm irregular nonbleeding necrotic ulcer in the gastric body on esophagogastroduodenoscopy. Biopsy and pathologic examination of the tissue indicated infection with a ra...

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Autores principales: Worrall, Emily B., Chhaparia, Anuj, Carpenter, Danielle, Neuschwander-Tetri, Brent A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436274/
https://www.ncbi.nlm.nih.gov/pubmed/36061245
http://dx.doi.org/10.14309/crj.0000000000000846
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author Worrall, Emily B.
Chhaparia, Anuj
Carpenter, Danielle
Neuschwander-Tetri, Brent A.
author_facet Worrall, Emily B.
Chhaparia, Anuj
Carpenter, Danielle
Neuschwander-Tetri, Brent A.
author_sort Worrall, Emily B.
collection PubMed
description We describe a patient who presented with hematemesis and was found to have unusually well-demarcated erythematous mucosa with a 2–3 cm irregular nonbleeding necrotic ulcer in the gastric body on esophagogastroduodenoscopy. Biopsy and pathologic examination of the tissue indicated infection with a rare bacterium, Sarcina ventriculi, prompting treatment with an unproven combination of 4 agents: metronidazole, ciprofloxacin, sucralfate, and pantoprazole. Repeat esophagogastroduodenoscopy 8 weeks later revealed complete resolution of the ulceration and surrounding erythema. These results may contribute toward establishing an appropriate therapeutic regimen for future S. ventriculi infections.
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spelling pubmed-94362742022-09-02 A Rare Cause of Upper Gastrointestinal Bleeding: Sarcina ventriculi Worrall, Emily B. Chhaparia, Anuj Carpenter, Danielle Neuschwander-Tetri, Brent A. ACG Case Rep J Case Report We describe a patient who presented with hematemesis and was found to have unusually well-demarcated erythematous mucosa with a 2–3 cm irregular nonbleeding necrotic ulcer in the gastric body on esophagogastroduodenoscopy. Biopsy and pathologic examination of the tissue indicated infection with a rare bacterium, Sarcina ventriculi, prompting treatment with an unproven combination of 4 agents: metronidazole, ciprofloxacin, sucralfate, and pantoprazole. Repeat esophagogastroduodenoscopy 8 weeks later revealed complete resolution of the ulceration and surrounding erythema. These results may contribute toward establishing an appropriate therapeutic regimen for future S. ventriculi infections. Wolters Kluwer 2022-08-31 /pmc/articles/PMC9436274/ /pubmed/36061245 http://dx.doi.org/10.14309/crj.0000000000000846 Text en © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Worrall, Emily B.
Chhaparia, Anuj
Carpenter, Danielle
Neuschwander-Tetri, Brent A.
A Rare Cause of Upper Gastrointestinal Bleeding: Sarcina ventriculi
title A Rare Cause of Upper Gastrointestinal Bleeding: Sarcina ventriculi
title_full A Rare Cause of Upper Gastrointestinal Bleeding: Sarcina ventriculi
title_fullStr A Rare Cause of Upper Gastrointestinal Bleeding: Sarcina ventriculi
title_full_unstemmed A Rare Cause of Upper Gastrointestinal Bleeding: Sarcina ventriculi
title_short A Rare Cause of Upper Gastrointestinal Bleeding: Sarcina ventriculi
title_sort rare cause of upper gastrointestinal bleeding: sarcina ventriculi
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436274/
https://www.ncbi.nlm.nih.gov/pubmed/36061245
http://dx.doi.org/10.14309/crj.0000000000000846
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