Altered excitatory and inhibitory neocortical circuitry leads to increased convulsive severity after pentylenetetrazol injection in an animal model of schizencephaly, but not of microgyria

OBJECTIVE: Malformations of the polymicrogyria spectrum can be mimicked in rodents through neonatal transcranial focal cortical freeze lesions. The animals presenting the malformations present both altered synaptic events and epileptiform activity in the vicinity of the microgyrus, but the comprehen...

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Detalles Bibliográficos
Autores principales: dos Santos Heringer, Luiza, Rios Carvalho, Julia, Teixeira Oliveira, Julia, Texeira Silva, Bruna, de Souza Aguiar dos Santos, Domethila Mariano, Martinez Martinez Toledo, Anna Lecticia, Borges Savoldi, Laura Maria, Magalhães Portela, Debora, Adriani Marques, Suelen, Campello Costa Lopes, Paula, Blanco Martinez, Ana Maria, Rocha Mendonça, Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436300/
https://www.ncbi.nlm.nih.gov/pubmed/35808864
http://dx.doi.org/10.1002/epi4.12625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436300/
https://www.ncbi.nlm.nih.gov/pubmed/35808864
http://dx.doi.org/10.1002/epi4.12625

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