Stroke-associated intergenic variants modulate a human FOXF2 transcriptional enhancer

SNPs associated with human stroke risk have been identified in the intergenic region between Forkhead family transcription factors FOXF2 and FOXQ1, but we lack a mechanism for the association. FoxF2 is expressed in vascular mural pericytes and is important for maintaining pericyte number and stabili...

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Detalles Bibliográficos
Autores principales: Ryu, Jae-Ryeon, Ahuja, Suchit, Arnold, Corey R., Potts, Kyle G., Mishra, Aniket, Yang, Qiong, Sargurupremraj, Muralidharan, Mahoney, Douglas J., Seshadri, Sudha, Debette, Stéphanie, Childs, Sarah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436329/
https://www.ncbi.nlm.nih.gov/pubmed/35994645
http://dx.doi.org/10.1073/pnas.2121333119

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