Will microfluidics enable functionally integrated biohybrid robots?

The next robotics frontier will be led by biohybrids. Capable biohybrid robots require microfluidics to sustain, improve, and scale the architectural complexity of their core ingredient: biological tissues. Advances in microfluidics have already revolutionized disease modeling and drug development,...

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Detalles Bibliográficos
Autores principales: Filippi, Miriam, Yasa, Oncay, Kamm, Roger Dale, Raman, Ritu, Katzschmann, Robert K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436346/
https://www.ncbi.nlm.nih.gov/pubmed/36001689
http://dx.doi.org/10.1073/pnas.2200741119
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author Filippi, Miriam
Yasa, Oncay
Kamm, Roger Dale
Raman, Ritu
Katzschmann, Robert K.
author_facet Filippi, Miriam
Yasa, Oncay
Kamm, Roger Dale
Raman, Ritu
Katzschmann, Robert K.
author_sort Filippi, Miriam
collection PubMed
description The next robotics frontier will be led by biohybrids. Capable biohybrid robots require microfluidics to sustain, improve, and scale the architectural complexity of their core ingredient: biological tissues. Advances in microfluidics have already revolutionized disease modeling and drug development, and are positioned to impact regenerative medicine but have yet to apply to biohybrids. Fusing microfluidics with living materials will improve tissue perfusion and maturation, and enable precise patterning of sensing, processing, and control elements. This perspective suggests future developments in advanced biohybrids.
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spelling pubmed-94363462023-02-24 Will microfluidics enable functionally integrated biohybrid robots? Filippi, Miriam Yasa, Oncay Kamm, Roger Dale Raman, Ritu Katzschmann, Robert K. Proc Natl Acad Sci U S A Perspective The next robotics frontier will be led by biohybrids. Capable biohybrid robots require microfluidics to sustain, improve, and scale the architectural complexity of their core ingredient: biological tissues. Advances in microfluidics have already revolutionized disease modeling and drug development, and are positioned to impact regenerative medicine but have yet to apply to biohybrids. Fusing microfluidics with living materials will improve tissue perfusion and maturation, and enable precise patterning of sensing, processing, and control elements. This perspective suggests future developments in advanced biohybrids. National Academy of Sciences 2022-08-24 2022-08-30 /pmc/articles/PMC9436346/ /pubmed/36001689 http://dx.doi.org/10.1073/pnas.2200741119 Text en Copyright © 2022 the Author(s). Published by PNAS. https://creativecommons.org/licenses/by-nc-nd/4.0/This article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Perspective
Filippi, Miriam
Yasa, Oncay
Kamm, Roger Dale
Raman, Ritu
Katzschmann, Robert K.
Will microfluidics enable functionally integrated biohybrid robots?
title Will microfluidics enable functionally integrated biohybrid robots?
title_full Will microfluidics enable functionally integrated biohybrid robots?
title_fullStr Will microfluidics enable functionally integrated biohybrid robots?
title_full_unstemmed Will microfluidics enable functionally integrated biohybrid robots?
title_short Will microfluidics enable functionally integrated biohybrid robots?
title_sort will microfluidics enable functionally integrated biohybrid robots?
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436346/
https://www.ncbi.nlm.nih.gov/pubmed/36001689
http://dx.doi.org/10.1073/pnas.2200741119
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