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NAD(+) metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity

Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). Astrocytes are the most abundant glial cells in the CNS, and their dysfunction contributes to the pathogenesis of MS and its animal model, experimental autoimmune encephalomyelitis (EAE). Recent advances h...

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Detalles Bibliográficos
Autores principales:	Meyer, Tom, Shimon, Dor, Youssef, Sawsan, Yankovitz, Gal, Tessler, Adi, Chernobylsky, Tom, Gaoni-Yogev, Anat, Perelroizen, Rita, Budick-Harmelin, Noga, Steinman, Lawrence, Mayo, Lior
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436380/ https://www.ncbi.nlm.nih.gov/pubmed/35994674 http://dx.doi.org/10.1073/pnas.2211310119

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