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Drug-induced tumor-specific cytotoxicity in a whole tissue ex vivo model of human pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer. PDAC has a dismal prognosis and an inherent resistance to cytostatic drugs. The lack of reliable experimental models is a severe limitation for drug development targeting PDAC. We have employed a whole tissue ex vi...

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Detalles Bibliográficos
Autores principales:	Moro, Carlos Fernández, Selvam, Arun Kumar, Ghaderi, Mehran, Pimenoff, Ville N., Gerling, Marco, Bozóky, Béla, Elduayen, Soledad Pouso, Dillner, Joakim, Björnstedt, Mikael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436406/ https://www.ncbi.nlm.nih.gov/pubmed/36059619 http://dx.doi.org/10.3389/fonc.2022.965182

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