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Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report
INTRODUCTION: Acute presentation of multiple myeloma in the emergency department (ED) is an uncommon yet life-threatening clinical entity. CASE REPORT: A 42-year-old male presented to the ED with severe generalized fatigue and vision changes most notable in his left eye. Bilateral central retinal ve...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436500/ https://www.ncbi.nlm.nih.gov/pubmed/36049195 http://dx.doi.org/10.5811/cpcem.2022.4.55710 |
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author | Tandlich, Michael Andrew Williamson, Kelly |
author_facet | Tandlich, Michael Andrew Williamson, Kelly |
author_sort | Tandlich, Michael Andrew |
collection | PubMed |
description | INTRODUCTION: Acute presentation of multiple myeloma in the emergency department (ED) is an uncommon yet life-threatening clinical entity. CASE REPORT: A 42-year-old male presented to the ED with severe generalized fatigue and vision changes most notable in his left eye. Bilateral central retinal vein occlusion (CRVO) was diagnosed on dilated fundus exam in the ED. CONCLUSION: The most common cause of CRVO in adults over age 50 is vascular disease, but in younger adults, conditions of systemic inflammation or hyperviscosity must be considered. Diagnosis of CRVO requires emergent ophthalmology consultation and further treatment with phototherapy, steroids, and potentially anti-vascular endothelial growth factor. Ultimately, patients require hematology/oncology and ongoing management of acute hyperviscosity syndrome. We present this case to increase awareness surrounding this diagnosis among emergency physicians. Multiple myeloma should be considered in young patients who present to the ED with bilateral CRVO, acute renal failure, and symptomatic anemia. |
format | Online Article Text |
id | pubmed-9436500 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-94365002022-09-02 Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report Tandlich, Michael Andrew Williamson, Kelly Clin Pract Cases Emerg Med Case Report INTRODUCTION: Acute presentation of multiple myeloma in the emergency department (ED) is an uncommon yet life-threatening clinical entity. CASE REPORT: A 42-year-old male presented to the ED with severe generalized fatigue and vision changes most notable in his left eye. Bilateral central retinal vein occlusion (CRVO) was diagnosed on dilated fundus exam in the ED. CONCLUSION: The most common cause of CRVO in adults over age 50 is vascular disease, but in younger adults, conditions of systemic inflammation or hyperviscosity must be considered. Diagnosis of CRVO requires emergent ophthalmology consultation and further treatment with phototherapy, steroids, and potentially anti-vascular endothelial growth factor. Ultimately, patients require hematology/oncology and ongoing management of acute hyperviscosity syndrome. We present this case to increase awareness surrounding this diagnosis among emergency physicians. Multiple myeloma should be considered in young patients who present to the ED with bilateral CRVO, acute renal failure, and symptomatic anemia. University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine 2022-07-27 /pmc/articles/PMC9436500/ /pubmed/36049195 http://dx.doi.org/10.5811/cpcem.2022.4.55710 Text en © 2022 Tandlich. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) License. See: http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Case Report Tandlich, Michael Andrew Williamson, Kelly Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report |
title | Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report |
title_full | Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report |
title_fullStr | Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report |
title_full_unstemmed | Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report |
title_short | Bilateral Central Retinal Vein Occlusion as a First Presentation of Multiple Myeloma: A Case Report |
title_sort | bilateral central retinal vein occlusion as a first presentation of multiple myeloma: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436500/ https://www.ncbi.nlm.nih.gov/pubmed/36049195 http://dx.doi.org/10.5811/cpcem.2022.4.55710 |
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